Document Details Document Type : Article In Journal  Document Title : Chemoembolization in Metastatic Liver Neoplasms: KADR Experience Chemoembolization in Metastatic Liver Neoplasms: KADR Experience   Subject : Oncology  Document Language : English  Abstract : Objective To assess the results of chemoembolization in this pilot study for patients with unresetable metastatic liver neoplasms. Methods: Patients with unresectable liver metastases secondary to different primary tumors who did not have decompesated liver disease underwent selective intra-arterial chemotherapy consisting of 5-flourouracil, adriamycin and cisplatin followed by embolization of the fee4ing artery using Poly Vinyl Alcohol Particles (PVAP). Courses of treatment were given every four to six weeks for a minimum of three courses. Results: Eight patients with bilateral multiple or diffuse liver metastasis underwent chemoembolization. Five oUt of eight patients had good palliation of symptoms and improvement in their quality of life. Their average duration of palliation was 7.2 months. Median survival for all patients was seven months. Seven patients died within the first year from a diagnosis of liver metastasis. The last patient with carcinoid syndrome is still alive 36 months after diagnosis. Conclusion: Selective intra-arterial chemotherapy followed by embolizatiop in this pilot study with unresectable liver metastases gives palliation of symptoms and improvement in the quality of life for almost half of our patients but for a short duratiun. Patients with neuroendocrine tumors may have longer duration of palliation and survival. Further randomized trials with a higher numberof patients would be worthwhile pursuing  ISSN : 1319-1004  Journal Name : Medical Science Journal  Volume : 7  Issue Number : 1  Publishing Year : 1419 AH 1999 AD  Article Type : Article  Added Date : Thursday, April 19, 2012  Researchers Researcher Name (Arabic) Researcher Name (English) Researcher Type Dr Grade Email محمود الاحول AI-Ahwal, Mahmoud Investigator Doctorate   محمد رواس Rawas, Mohammad Researcher Doctorate   هشام أكبر Akbar, Hisham Researcher Doctorate   Files File Name Type Description  32916.pdf pdf   Back To Researches Page